Rainer Machauer Selected Research

NB-360

1/2019	The β-secretase (BACE) inhibitor NB-360 in preclinical models: From amyloid-β reduction to downstream disease-relevant effects.
9/2015	A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.

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Rainer Machauer Research Topics

Disease

5	Alzheimer Disease (Alzheimer's Disease) 10/2021 - 09/2015
3	Dementia (Dementias) 01/2019 - 09/2015
2	Neuroinflammatory Diseases 01/2019 - 09/2015
2	Leukemia 03/2017 - 08/2016
1	Asymptomatic Diseases 11/2018
1	Amyloid Plaque 11/2018
1	Neoplasms (Cancer) 08/2016

Drug/Important Bio-Agent (IBA)

4	Amyloid (Amyloid Fibrils)IBA 01/2019 - 09/2015
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2021 - 02/2016
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2016
2	UmibecestatIBA 10/2021 - 11/2018
2	NB-360IBA 01/2019 - 09/2015
2	Histone MethyltransferasesIBA 03/2017 - 08/2016
1	EnzymesIBA 01/2019
1	MethyltransferasesIBA 08/2016

Therapy/Procedure

2	Therapeutics 01/2019 - 11/2018
1	Precision Medicine 01/2019